Publications

Beta Living through Alpha Cells. Patzek S, Sneddon JB. Cell Stem Cell. 2019 Apr 4;24(4):503-505. doi: 10.1016/j.stem.2019.03.016

Pancreatic development: one cell at a (pseudo)time. Liu Z, Sneddon JB. EMBO J. 2019 Apr 15;38(8). pii: e101891. doi: 10.15252/embj.2019101891. Epub 2019 Mar 26.

Lineage dynamics of murine pancreatic development at single-cell resolution. Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB. Nat Commun. 2018 Sep 25;9(1):3922. doi: 10.1038/s41467-018-06176-3.

Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. J Clin Invest. 2018 Oct 1;128(10):4343-4358. doi: 10.1172/JCI99435. Epub 2018 Jul 12.

Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Cell Stem Cell. 2018 Jun 1;22(6):810-823. doi: 10.1016/j.stem.2018.05.016.

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Farmer DT, Nathan S, Finley JK, Shengyang Yu K, Emmerson E, Byrnes LE, Sneddon JB, McManus MT, Tward AD, Knox SM.Development. 2017 Jul 1;144(13):2517-2528. doi: 10.1242/dev.150789. Epub 2017 Jun 2.

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. Cheng CW, Villani V, Buono R, Wei M, Kumar S, Yilmaz OH, Cohen P, Sneddon JB, Perin L, Longo VD. Cell. 2017 Feb 23;168(5):775-788.e12. doi: 10.1016/j.cell.2017.01.040.

Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells. Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA. Stem Cells. 2013 Dec;31(12):2833-41. doi: 10.1002/stem.1445.

Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Sneddon JB, Borowiak M, Melton DA. Nature. 2012 Nov 29;491(7426):765-8. doi: 10.1038/nature11463. Epub 2012 Oct 7.

The contribution of niche-derived factors to the regulation of cancer cells. Sneddon JB. Methods Mol Biol. 2009;568:217-32. doi: 10.1007/978-1-59745-280-9_14.

Location, location, location: the cancer stem cell niche. Sneddon JB, Werb Z. Cell Stem Cell. 2007 Dec 13;1(6):607-11. doi: 10.1016/j.stem.2007.11.009.

The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Welm AL, Sneddon JB, Taylor C, Nuyten DS, van de Vijver MJ, Hasegawa BH, Bishop JM. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7570-5. Epub 2007 Apr 24.

When should one subtract background fluorescence in 2-color microarrays? Scharpf RB, Iacobuzio-Donahue CA, Sneddon JB, Parmigiani G. Biostatistics. 2007 Oct;8(4):695-707. Epub 2006 Dec 12.

Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Breast Cancer Res. 2006;8(5):R62.

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14842-7. Epub 2006 Sep 26.

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3738-43. Epub 2005 Feb 8.

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. PLoS Biol. 2004 Feb;2(2):E7. Epub 2004 Jan 13.